Platelet-Rich Fibrin (PRF)

Enhancing Healing Using Your Body’s Own Biology

Platelet-rich fibrin (PRF) is a regenerative treatment derived from your own blood, used to support healing following oral and maxillofacial surgical procedures.

It provides a concentrated source of platelets, growth factors, and fibrin, helping to enhance tissue repair, reduce inflammation, and support more predictable healing.


What Is PRF?

PRF is produced by taking a small sample of blood and processing it in a centrifuge.

This creates a natural matrix containing:

  • Platelets (which release growth factors)
  • White blood cells
  • A fibrin scaffold that supports tissue repair

Unlike some other preparations, PRF:

  • Does not require additives or chemicals
  • Forms a slow-release system for growth factors
  • Can be used as a membrane or mixed with graft materials

How PRF Works

PRF supports healing by:

  • Enhancing early wound stability
  • Promoting soft tissue healing
  • Supporting bone regeneration
  • Reducing inflammation within the surgical site

It acts as a biological scaffold, encouraging the body’s natural repair mechanisms.


Benefits of PRF

PRF offers several potential advantages:

  • Uses your own biological material
  • No risk of allergic reaction
  • Supports natural healing processes
  • May reduce swelling and discomfort
  • Helps create a more stable healing environment

It is used to optimise healing rather than replace surgical technique.


The PRF Process

PRF preparation is straightforward.

  • A small blood sample is taken at the time of surgery
  • It is processed immediately to produce PRF
  • The PRF is applied directly to the surgical site

Uses in Oral Surgery

PRF is used as an adjunct in a range of procedures, including:

Tooth Extractions

  • Improves healing of extraction sites
  • May reduce discomfort following surgery
  • Particularly useful in higher-risk extractions

Wisdom Tooth Surgery


Bone Grafting Procedures

  • Combined with bone graft materials to support bone regeneration
  • Improves graft handling and stability
  • Enhances integration of graft material

Implant Surgery

  • Used around dental implants to support healing
  • May improve early tissue response
  • Supports both hard and soft tissue integration

Management of Difficult Healing

  • Used in selected cases where healing may be slower
  • Can support tissue repair in compromised sites

Limitations and Expectations

PRF is an adjunct, not a substitute for surgery.

Its role is to support and enhance healing, rather than guarantee outcomes.


Risks and Considerations

PRF is derived from your own blood and is generally very safe.


Consultation

A consultation allows discussion of your procedure and whether adjunctive treatments such as PRF are appropriate.


Book a Consultation

For oral and maxillofacial surgical procedures in London, including those using PRF to support healing, arrange a consultation to discuss your treatment plan.

Book a Consultation

Written and medically reviewed by:

Dr Tom Pepper
Consultant Oral & Maxillofacial Surgeon
MBBS BDS MSc FRCS

GMC 7458325 GDC 83669

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